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Potential Biologically Active Agents, XXVII: Synthesis of Some 4-Substituted Phenylmercaptoacetic Acids

✍ Scribed by Rajendra S. Varma; Surendra Bahadur; Anil K. Agnihotri

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
242 KB
Volume
314
Category
Article
ISSN
0365-6233

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✦ Synopsis

Abstract

Condensation of 4‐(3__H__)‐quinazolinone (2) with 4‐(aminophenyl)‐mercaptoacetic acid under the conditions of the Mannich reaction furnished compounds 3a and 3b. Reaction of 4 with 4‐(amino‐phenyl)mercaptoacetic acid yielded 5 which when treated with aryl aldehydes gave 6. Similarly, compounds 8 were obtained from 7.

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