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Potential anxiolytic properties of R-(+)-8-OSO2CF3-PAT, a 5-HT1A receptor agonist

✍ Scribed by Tjeerd Barf; S.Mechiel Korte; Gerdien Korte-Bouws; Clas Sonesson; Geert Damsma; Béla Bohus; Håkan Wikström

Book ID
115890748
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
737 KB
Volume
297
Category
Article
ISSN
0014-2999

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✍ M. J. Ackland; L. G. Dring; J. R. Jones; N. Gilon 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 364 KB

## Abstract The title compounds were synthesised in 7 steps from 1,7‐dihydroxynaphthalene as follows: 1,7‐dihydroxynaphthalene was methylated and subjected to a Birch reduction to yield 8‐methoxy‐2‐tetralone. Reductive amination with sodium cyanoboro[^3^H]hydride and n‐propylamine gave 8‐methoxy‐2‐