Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication through Optimization of Indole- N -Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase
β Scribed by Harper, Steven; Avolio, Salvatore; Pacini, Barbara; Di Filippo, Marcello; Altamura, Sergio; Tomei, Licia; Paonessa, Giacomo; Di Marco, ; Carfi, Andrea; Giuliano, Claudio; Padron, Julio; Bonelli, Fabio; Migliaccio, Giovanni; De Francesco, Raffaele; Laufer, Ralph; Rowley, Michael; Narjes, Frank
- Book ID
- 120329521
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 260 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0022-2623
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract __Infections caused by the hepatitisβ C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The NS5B polymerase of HCV is responsible for the replication of viral RNA and has been a prime target in the search for novel treatment options. We