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Potent inhibition of respiratory syncytial virus by combination treatment with 2–5A antisense and ribavirin

✍ Scribed by Zan Xu; Mei Kuang; James R. Okicki; Hagen Cramer; Nilabh Chaudhary


Book ID
113457098
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
449 KB
Volume
61
Category
Article
ISSN
0166-3542

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R1626, a prodrug of the hepatitis C virus (HCV) RNA polymerase inhibitor R1479, showed time-dependent and dose-dependent reduction of HCV RNA levels in a previous study. The present study evaluated the efficacy and safety of R1626 administered for 4 weeks in combination with peginterferon alfa-2a ؎