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Potent induction therapy with interferon and ribavirin combination therapy does not achieve a higher sustained virological response rate in chronic hepatitis C with genotype 1b and high hepatitis C virus RNA level

✍ Scribed by Shotaro Enomoto; Hideyuki Tamai; Masashi Oka; Naoki Shingaki; Tatsuya Shiraki; Machiko Takeuchi; Hisanobu Deguchi; Hirohito Magari; Izumi Inoue; Mikitaka Iguchi; Kimihiko Yanaoka; Kenji Arii; Mitsuhiro Fujishiro; Naohisa Yahagi; Hiroshi Yotsuyanagi; Masao Ichinose


Book ID
118087811
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
134 KB
Volume
37
Category
Article
ISSN
1386-6346

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## Abstract Patients with high viral load (β‰₯1.0 × 10^5^ IU/ml) of hepatitis C virus (HCV) genotype 1b do not achieve high sustained virological response rates to interferon (IFN)/ribavirin combination therapy. Previous studies suggested that pretreatment amino acid (aa) substitution patterns in the