## Abstract The T cell surface protein CD28 provides a critical costimulatory signal for T cell activation. With age, humans accumulate increasing numbers of CD28^–^ T cells, and this loss of CD28 expression is exacerbated certain disease states, such as HIV infection, autoimmune conditions or canc
✦ LIBER ✦
Potent costimulation of human CD8 T cells by anti-4-1BB and anti-CD28 on synthetic artificial antigen presenting cells
✍ Scribed by Despina Rudolf; Tobias Silberzahn; Steffen Walter; Dominik Maurer; Johanna Engelhard; Dorothee Wernet; Hans-Jörg Bühring; Gundram Jung; Byoung S. Kwon; Hans-Georg Rammensee; Stefan Stevanović
- Book ID
- 105967281
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 546 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Costimulation of human CD28– T cells by
✍
Jacob Bukczynski; Tao Wen; Tania H. Watts
📂
Article
📅
2003
🏛
John Wiley and Sons
🌐
English
⚖ 305 KB
Murine CD8 lymphocyte expansion in vitro
✍
Xiaocai Yan; Bryon D. Johnson; Rimas J. Orentas
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 267 KB
Enhanced anti-tumor activity of interfer
✍
Kristan D. Guenterberg; Gregory B. Lesinski; Bethany L. Mundy-Bosse; Volodymyr I
📂
Article
📅
2011
🏛
Springer-Verlag
🌐
English
⚖ 353 KB
Surface antigens of human thymocyte popu
✍
Frank Sotzik; Andrew Boyd; Ken Shortman
📂
Article
📅
1993
🏛
Elsevier Science
🌐
English
⚖ 384 KB
Transplantation tolerance induced by ant
✍
Andrew Bushell; Peter J. Morris; Kathryn J. Wood
📂
Article
📅
1995
🏛
John Wiley and Sons
🌐
English
⚖ 761 KB
NK and CD8+ T cell-mediated eradication
✍
Dongping Xu; Peidi Gu; Ping-Ying Pan; Qingsheng Li; Alice I. Sato; Shu-Hsia Chen
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
French
⚖ 151 KB
## Abstract In previous reports, systemic administration of a stimulatory monoclonal antibody directed against the 4‐1BB receptor had no effect on survival or tumor burden in mice inoculated with the poorly immunogenic B16‐F10 melanoma. We combined IL‐12 gene transfer with 4‐1BB costimulation to ex