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Potent bronchoconstrictor effects of aerosolized prostaglandin D2 in dogs

โœ Scribed by Martin A. Wasserman; R.L. Griffin; F.B. Marsalisi

Book ID
119049001
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
480 KB
Volume
20
Category
Article
ISSN
0090-6980

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The effect of aerosolized SK&F 104353-Z2
The effect of aerosolized SK&F 104353-Z2 on the bronchoconstrictor effect of leukotriene D4 in asthmatics
โœ G.F. Joos; J.C. Kips; R.A. Pauwels; M.E. Van Der Straeten ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier ๐ŸŒ English โš– 494 KB

Leukotriene D4 (LTD4) is a potent bronchoconstrictor and vasoactive mediator that has been implicated in the pathogenesis of bronchial asthma. We have studied the effect of SK&F 104353-Z2, a specific LTD4 antagonist, on LTD4-induced bronchoconstriction in asthmatics. A total of 12 mild asthmatics (m