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Potassium fluoride assisted derivatization of carboxylic acids to phenacyl esters for determination by high-performance liquid chromatography

โœ Scribed by Miller, Jack M.; Brindle, Ian D.; Cater, Stephen R.; So, Kwok-Hung.; Clark, James H.


Book ID
127200305
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
371 KB
Volume
52
Category
Article
ISSN
0003-2700

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The use of 4'-bromo-2-hydroxyacetophenone trifluoromethanesulfonate ester (4'-bromophenacyl triflate) in the preparation of carboxylic acid 4'-bromophenacyl ester derivatives for spectrophotometric detection in high-performance liquid chromatography is described. The reagent is prepared in 66% yield