## Abstract Ca^2+^‐activated K^+^ (K~Ca~) channels are a unique family of ion channels because they are capable of directly communicating calcium signals to changes in cell membrane potential required for cellular processes including but not limited to cellular proliferation and migration. It is no
Potassium channels in human glioma cells
✍ Scribed by T. Brismar; V. P. Collins
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 131 KB
- Volume
- 414
- Category
- Article
- ISSN
- 0031-6768
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Voltage‐dependent large‐conductance Ca^2+^‐activated K^+^ channels, often referred to as __BK channels__, are a unique class of ion channels coupling intracellular chemical signaling to electrical signaling. BK channel expression has been shown to be up‐regulated in human glioma biopsie
## Abstract We have previously demonstrated the expression of large‐conductance, calcium‐activated potassium (BK) channels in human glioma cells. In the present study, we characterized the calcium sensitivity of glioma BK channels in excised membrane patches. Channels in inside‐out patches were act
Unitary currents through single ion channels in the glial cells, which ensheath the abdominal stretch receptor neurons of the crayfish, were characterized with respect to their basic kinetic properties. In cell-attached and excised patches two types of Ca+ +-independent K+ channels were observed wit
## Abstract Potassium channels, the most diverse superfamily of ion channels, have recently emerged as regulators of carcinogenesis, thus introducing possible new therapeutic strategies in the fight against cancer. In particular, the large conductance Ca^2+^‐activated K^+^ channels, often referred
Endogenous voltage-gated potassium currents were investigated in human embryonic kidney (HEK293) and Chinese hamster ovary (CHO) cells using wholecell voltage clamp recording. Depolarizing voltage steps from ؊70 mV triggered an outwardly rectified current in nontransfected HEK293 cells. This current