Potassium carbonate, a support for the green synthesis of azoles and diazines

✍ Scribed by M. Kidwai; R. Venkataramanan; B. Dave

• Book ID: 102339902
• Publisher: Journal of Heterocyclic Chemistry
• Year: 2002
• Tongue: English
• Weight: 27 KB
• Volume: 39
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570390530

✦ Synopsis

Abstract

A novel potassium carbonate mediated synthesis of 2‐amino‐1,3‐thia/oxa zoles, 2‐amino‐1,3,4‐thia/oxa diazines and 2‐hydrazino‐1,3,4‐thiadiazines has been described here. The use of K~2~CO~3~ allows for an aqueous workup thereby eliminating the organic solvent from both the reaction step and post reaction stage, without compromising the yield and reaction time.