Posttranslational modifications of α-tubulin ofToxoplasma gondii
✍ Scribed by Uwe Plessmann; Ingrid Reiter-Owona; Karl-Ferdinand Lechtreck
- Book ID
- 106127808
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 442 KB
- Volume
- 94
- Category
- Article
- ISSN
- 1432-1955
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📜 SIMILAR VOLUMES
We describe the presence of alpha-tubulin and MAP2 acetyltransferase activities in mouse brain. The enzyme(s) copurified with microtubules through two cycles of assembly-disassembly. Incubation of microtubule proteins with [3H]acetyl CoA resulted in a strong labeling of both alpha-tubulin and MAP2.
In cold poikilotherm organisms, microtubule assembly is promoted at temperatures below 4°C and cold-induced depolymerization is prevented. On the basis of the results of investigations on cold-adapted fishes, the property of cold adaptation is ascribed to intrinsic characteristics of the tubulins. T