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Posttranslational Mechanisms Control the Timing of bHLH Function and Regulate Retinal Cell Fate

โœ Scribed by Kathryn B. Moore; Meredith L. Schneider; Monica L. Vetter


Book ID
117608165
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
681 KB
Volume
34
Category
Article
ISSN
0896-6273

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Hairy-related proteins are a distinct subfamily of basic helix-loop-helix (bHLH) proteins that generally function as DNA-binding transcriptional repressors. These proteins act in opposition to bHLH transcriptional activator proteins such as the proneural and myogenic proteins; together, the activato