## Abstract Schwann cells within a peripheral nerve respond robustly after an axonal injury. Recent results have revealed that Schwann cells undergo concurrent proliferation and apoptosis after a chronic nerve injury that is independent of axonal pathology. Although the exact nature of the stimulus
Posttranslational Degradation of the Major Myelin Glycoprotein by Schwann Cells in Vivo and in Vitro
โ Scribed by KURT R. BRUNDEN; JOSEPH F. PODUSLO
- Book ID
- 119865253
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 908 KB
- Volume
- 605
- Category
- Article
- ISSN
- 0890-6564
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The interaction of the Schwann cell with its basal lamina has been hypothesized to be an important prerequisite for the formation of a myelin sheath in the peripheral nervous system. One possible player in this interaction is โค4 integrin; it is up-regulated during myelin formation and, in associatio
The adult cat sciatic nerve was examined for Schwann cell biosynthesis of the major myelin glycoprotcin (Po) in the distal segments after permanent nerve transection, where there is no axonal regeneration or myelin assembly. Endoneurial slices (intrafascicular tissue) from the distal segment of the