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Posttranscriptional Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Lens Epithelial Cells by Mevalonate-Derived Nonsterols

✍ Scribed by RICHARD J. CENEDELLA

Book ID
115605135
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
326 KB
Volume
65
Category
Article
ISSN
0014-4835

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## Abstract Elevated 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase expression supports synthesis of prenyl pyrophosphate intermediates required for tumor growth. In this study, the copy number of HMG‐CoA reductase mRNA was determined in solid tumor and leukemic cell lines using competit