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Postsynaptic 5-HT1Areceptors mediate an increase in locomotor activity in the monoamine-depleted rat

✍ Scribed by Laurence Mignon; William A. Wolf

Publisher
Springer
Year
2002
Tongue
English
Weight
141 KB
Volume
163
Category
Article
ISSN
0033-3158

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## Abstract Excessive glutamate transmission in the basal ganglia is a major factor in the neural mechanisms underlying parkinsonian akinesia. Activation of K opioid receptors causes a presynaptic reduction in glutamate release. K opioid receptors are concentrated in those regions of the basal gang