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Postoperative radiotherapy for primary early oral tongue cancer with pathologic N1 neck

✍ Scribed by Tseng-Cheng Chen; Chi-Te Wang; Jenq-Yuh Ko; Pei-Jen Lou; Tsung-Lin Yang; Lai-Lei Ting; Chun-Wei Wang; Ya-Ling Hu; Cheng-Ping Wang

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 192 KB
Volume: 32
Category: Article
ISSN: 1043-3074
DOI: 10.1002/hed.21217

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background

The benefit of postoperative radiotherapy (PORT) for early squamous cell carcinoma of the tongue (SCCOT) with pathologic N1 disease remains unclear.

Methods

The medical records of all patients with pathologic T1‐2/N0‐1 SCCOT who underwent wide excision of the primary tumor and neck dissection between 1980 and 2002 were reviewed.

Results

There were 59 patients analyzed, including 28 patients with and 31 patients without PORT. The 5‐year disease‐free survival rates were 81.2% and 53% for the patients with and without PORT, respectively (p = .03). The overall 5‐year survival rates were 77% and 70.5% for the patients with and without PORT, respectively (p = .36). Multivariate analyses showed that PORT had the only protective effect (p = .01) and extracapsular spread (ECS) was the only significantly adverse factor for locoregional recurrence (p = .03).

Conclusions

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