Neuraxis radiation therapy (RT) for primary intracranial tumors is associated with major late effects if administered to very young children. To control residual tumor and to delay RT, we treated eight young children (median age 6.5 months) with primary central nervous system (CNS) tumors using comb
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Postoperative chemotherapy without radiation in young children with malignant non-astrocytic brain tumours
โ Scribed by Les White; Heather Johnston; Robert Jones; Hedy Mameghan; Vim Nayanar; William McWhirter; Stuart Kellie; Keith Waters; Ian Toogood
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 453 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0344-5704
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## Background: Chemotherapy may be used to delay the need for cranial irradiation in infants and young children with malignant central nervous system (cns) tumors. the polyfunctional alkylator thiotepa (tt) possesses significant in vitro and in vivo activity in many central nervous system tumors. b