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Postnatal development of nitric oxide synthase activity in fast and slow muscles of the rat

✍ Scribed by Jill Lincoln; Rehab Harb

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
89 KB
Volume
21
Category
Article
ISSN
0148-639X

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✦ Synopsis

Nitric oxide synthase (NOS) activity was measured in extensor digitorum longus (EDL) and soleus muscles during postnatal development in the rat. At 1 and 2 weeks of age, similar low levels were found in both muscles. After 2 weeks, activity increased significantly only in EDL. Adult NOS activity was significantly higher in EDL than soleus. Thus, the preferential expression of NOS in fast muscle only occurs once the adult pattern of motor activity is established.

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## Background: The presence of nitric-oxide-synthesising neurons in the adrenal gland has recently been described by the immunohistochemical and/or enzyme histochemical demonstration of its synthesising enzyme, nitric oxide synthase (nos; afework et al. 1994. cell tissue res,276:133-141). in the pr