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Postnatal decrease of acetate concentration in rat cerebellum

✍ Scribed by M. Martin; M. Merele; J. Labouesse; P. Canioni


Book ID
102386172
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
404 KB
Volume
37
Category
Article
ISSN
0360-4012

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✦ Synopsis


Abstract

We examined the evolution of ^1^H‐NMR detectable metabolites in rat cerebellum fro the postnatal day 1–25, a period associated with intense metabolic changes as well as physiological and morphological modifications. The unexpected result reported here is the existence of a high concentration of acetate in neonatal rat cerebellum, progressively decreasing with age and maturation. In contrast, the cerebellum content of various metabolites such as N‐acetyl‐L‐as‐partate (NAA), glutamate, and aspartate increases from the first day onward. © 1994 Wiley‐Liss, Inc.


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