Postnatal decrease of acetate concentration in rat cerebellum
✍ Scribed by M. Martin; M. Merele; J. Labouesse; P. Canioni
- Book ID
- 102386172
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 404 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0360-4012
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✦ Synopsis
Abstract
We examined the evolution of ^1^H‐NMR detectable metabolites in rat cerebellum fro the postnatal day 1–25, a period associated with intense metabolic changes as well as physiological and morphological modifications. The unexpected result reported here is the existence of a high concentration of acetate in neonatal rat cerebellum, progressively decreasing with age and maturation. In contrast, the cerebellum content of various metabolites such as N‐acetyl‐L‐as‐partate (NAA), glutamate, and aspartate increases from the first day onward. © 1994 Wiley‐Liss, Inc.
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