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Postmortem cerebral cortex Gs α-subunit levels are elevated in bipolar affective disorder

✍ Scribed by L.T. Young; P.P. Li; S.J. Kish; K.P. Siu; J.J. Warsh


Book ID
115801871
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
640 KB
Volume
553
Category
Article
ISSN
0006-8993

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## Abstract Reports of elevated Gs α subunit (α~s~) immunolabeling and cAMP‐mediated hyper‐functionality in autopsied cerebral cortical brain regions from bipolar affective disorder (BD) patients suggest signal transduction abnormalities occur in this disorder. Because covalent modification of α~s~