Postischemic Blockade of AMPA but not NMDA Receptors Mitigates Neuronal Damage in the Rat Brain Following Transient Severe Cerebral Ischemia

Moderate hypothermia mitigates neuronal

Moderate hypothermia mitigates neuronal damage in the rat brain when initiated several hours following transient cerebral ischemia

✍ Cicero Coimbra; Tadeusz Wieloch 📂 Article 📅 1994 🏛 Springer-Verlag 🌐 English ⚖ 796 KB

Intra-ischemic moderate hypothermia generally protects the brain against ischemic cell death, while hypothermia instigated several hours into the reperfusion phase is considered to be less effective. Here we report the effect of hypothermia (32.5 degrees - 33.5 degrees C) of 5-h duration, initiated