This study was designed to investigate the efficacy of the antidepressant fluvoxamine in the treatment of combat-related post-traumatic stress disorder (PTSD). Fifteen veterans with combat-related PTSD and no other psychiatric diagnosis except depression were recruited to participate in a 14-week op
Post-traumatic stress disorder and prediction of aggression in persons with dementia
β Scribed by Valdesha L. Ball; Sonora Hudson; Jessica Davila; Robert Morgan; Annette Walder; David P. Graham; Andrea L. Snow; Mark E. Kunik
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 74 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0885-6230
- DOI
- 10.1002/gps.2258
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Objective
This prospective cohort study evaluated the potential of increased aggression in patients with dementia who had a preexisting diagnosis of postβtraumatic stress disorder (PTSD) compared with those without a diagnosis of PTSD.
Methods
Patients more than 60βyears of age with newly diagnosed dementia between 2001 and 2004 were identified from the Michael E. DeBakey Veterans Affairs (VA) Medical Center in Houston, TX. Among these patients, we identified patients with a preexisting diagnosis of PTSD. The proportions of patients who became aggressive within 2βyears of enrollment were compared in patients with and without PTSD. Fisher's exact tests were used to compare differences in the number of PTSD patients with and without aggression.
Results
A total of 215 patients were identified with newly diagnosed dementia. Ten were found to have a diagnosis of PTSD, and 205 did not. Eightyβfour (41%) of the 205 were found to be aggressive. Among the 10 patients with a diagnosis of PTSD, 4 (40%) were aggressive.
Conclusion
There was no evidence to support an increased risk of aggression in patients with a coexisting diagnosis of dementia and PTSD. Copyright Β© 2009 John Wiley & Sons, Ltd.
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