Post-Traumatic Arthritis. Diagnosis, Man
β Savyasachi C. Thakkar, Erik A. Hasenboehler (ed.)
π Library
π
2021
π Springer
π English
β¦ LIBER β¦
π
Post-Traumatic Arthritis: Pathogenesis, Diagnosis and Management
β Scribed by Steven A. Olson, MD, Farshid Guilak, PhD (eds.)
- Publisher
- Springer US
- Year
- 2015
- Tongue
- English
- Leaves
- 362
- Edition
- 1
- Category
- Library
β¬ Acquire This Volume
No coin nor oath required. For personal study only.
β¦ Synopsis
Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-articular tissue responses to of joint injury and potential mechanisms of PTA; the current clinical assessment and treatment of common joint injuries leading to PTA; and emerging technologies and treatments for PTA, including biomarkers and stem cell therapies. Taken together, it will be an invaluable resource for orthopedic surgeons, rheumatologists and other joint injury researchers and clinicians.
β¦ Table of Contents
Front Matter....Pages i-xx
Front Matter....Pages 1-1
Arthritis That Develops After Joint Injury: Is It Post-Traumatic Arthritis or Post-Traumatic Osteoarthritis?....Pages 3-6
Post-Traumatic Arthritis: Definitions and Burden of Disease....Pages 7-15
Arthritis After Joint Injury: The Military Experience....Pages 17-26
Front Matter....Pages 27-27
In Vitro Cartilage Explant Injury Models....Pages 29-40
Animal Models of Meniscal Injury in Post-Traumatic Arthritis....Pages 41-62
Anterior Cruciate Transection/Disruption Models of Post-Traumatic Arthritis....Pages 63-74
Closed Joint ACL Disruption Murine Model of PTA....Pages 75-85
Whole Joint Models of Articular Injury and Articular Fracture....Pages 87-100
Instability: Dynamic Loading Models....Pages 101-112
Survey of Animal Models in Post-Traumatic Arthritis: Choosing the Right Model to Answer the Right Question....Pages 113-118
Front Matter....Pages 119-119
The Response of Cartilage to Injury....Pages 121-133
The Response of the Subchondral Bone to Injury....Pages 135-147
Genetic Variability in the Response to Injury....Pages 149-164
Aging and Post-Traumatic Arthritis....Pages 165-183
Potential Mechanisms of PTA: Cell Death....Pages 185-199
Potential Mechanisms of PTOA: Inflammation....Pages 201-209
Potential Mechanisms of PTA: Oxidative Stress....Pages 211-219
Potential Mechanism of PTA: Alterations in Joint Loading....Pages 221-233
Front Matter....Pages 235-235
Imaging Specific to Cartilage Injury....Pages 237-257
Outcomes of ACL Injury: The MOON Consortium....Pages 259-268
Front Matter....Pages 235-235
Current Treatment and Outcomes of Intra-articular Fractures....Pages 269-283
Non-arthroplasty Treatments for PTA in the Lower Extremity....Pages 285-293
Results of Arthroplasty in Post-Traumatic Arthritis....Pages 295-301
Front Matter....Pages 303-303
Measurement of Severity of Injury After Articular Fracture and Correlation with Post-Traumatic Arthritis Development....Pages 305-315
Biomarkers of PTA....Pages 317-330
Potential Targets for Pharmacologic Therapies for Prevention of PTA....Pages 331-342
Stem Cell Therapies for Post-Traumatic Arthritis....Pages 343-348
Unanswered Questions and Future Directions in Post-Traumatic Arthritis....Pages 349-352
Back Matter....Pages 353-360
β¦ Subjects
Orthopedics; Rheumatology; Sports Medicine
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