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Post-translational modifications of rat liver mitochondrial outer membrane proteins identified by mass spectrometry

✍ Scribed by Anne M. Distler; Janos Kerner; Charles L. Hoppel


Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
492 KB
Volume
1774
Category
Article
ISSN
1570-9639

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## Abstract The modification of mitochondrial proteins enriched from rat forebrain by the major lipid peroxidation product 4‐hydroxy‐2‐nonenal (HNE) was investigated using high performance liquid chromatography (HPLC) and tandem mass spectrometry. Subcellular fractionation in conjunction with a β€˜sh