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Post-translational modification of NMDA receptor GluN2B subunit and its roles in chronic pain and memory

✍ Scribed by Shuang Qiu; Xiang-Yao Li; Min Zhuo


Book ID
116881697
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
865 KB
Volume
22
Category
Article
ISSN
1084-9521

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## Abstract Benzodiazepine withdrawal‐anxiety is associated with enhanced α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid receptor (AMPAR)‐mediated glutamatergic transmission in rat hippocampal CA1 synapses due to enhanced synaptic insertion and phosphorylation of GluA1 homomers. Interestingly