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Post-transcriptional regulation of placenta growth factor mRNA by hydrogen peroxide

✍ Scribed by Jennifer H. Shaw; Pamela G. Lloyd


Book ID
119330798
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
610 KB
Volume
84
Category
Article
ISSN
0026-2862

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## Abstract PTEN is a critical tumor suppressor gene mutated frequently in various human cancers. Previous studies have showed that PTEN mRNA expression is down‐regulated by TGF‐β1 in various cell lines. In present study, we have found that TGF‐β1 down‐regulates PTEN mRNA and protein expression in