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Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7α-hydroxylase in rats with subtotal nephrectomy

✍ Scribed by Pandak, William M; Vlahcevic, Z Reno; Heuman, D M; Krieg, Richard J; Hanna, James D; Chan, James C M

Book ID
109883756
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
722 KB
Volume
46
Category
Article
ISSN
0085-2538

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We investigated hepatic cholesterol homeostasis in four homozygous sitosterolemic subjects from two unrelated families who showed enhanced absorption, diminished removal and increased tissue and plasma concentrations of sitosterol (24-ethyl cholesterol). Measurements of hepatic 3-hydroxy-3-methylglu