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Post-Natal Ontogenesis of the T-Cell Receptor CD4 and CD8 Vβ Repertoire and Immune Function in Children with DiGeorge Syndrome

✍ Scribed by Caterina Cancrini; Maria Luisa Romiti; Andrea Finocchi; Silvia Di Cesare; Patrizia Ciaffi; Claudia Capponi; Savita Pahwa; Paolo Rossi


Publisher
Springer
Year
2005
Tongue
English
Weight
151 KB
Volume
25
Category
Article
ISSN
0271-9142

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The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of a and p variable region chains present in the T cell receptor complex. Currently, the Vp chains are grouped into 25 families. Historically, determination of Vp usage has relied on d