Possible use of combination chemotherapy with mitomycin C and methotrexate for metastatic breast cancer pretreated with anthracycline and taxanes
โ Scribed by Masahiko Tanabe; Yoshinori Ito; Nahomi Tokudome; Tsutomu Sugihara; Hiroyoshi Miura; Shunji Takahashi; Yasuyuki Seto; Takuji Iwase; Kiyohiko Hatake
- Book ID
- 107643721
- Publisher
- Springer Japan
- Year
- 2009
- Tongue
- English
- Weight
- 174 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1340-6868
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๐ SIMILAR VOLUMES
Twenty-nine patients with metastatic breast cancer were treated with fluorouracil, adriamycin, cyclophosphamide (FAC), and methotrexate (MTX), with or without leukovorin rescue. Of 24 evaluable patients, one achieved a complete remission and 17 had partial responses. The overall objective response r
Fifty-seven patients with metastatic breast carcinoma have been treated with mitomycin C (10 mg/m2 IV 6-weekly), melphalan (6 mg/m2 PO X 3 days, 3-weekly), and methotrexate (35 mg/m2 IV 3-weekly) to assess the efficacy and toxicity of this regimen. Of 48 evaluable patients 19 (40%) responded for a m