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Possible role of procathepsin D in human cancer

✍ Scribed by A. Vashishta; M. Fusek; V. Větvička


Book ID
105660978
Publisher
Springer Netherlands
Year
2005
Tongue
English
Weight
183 KB
Volume
50
Category
Article
ISSN
0015-5632

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Cathepsin D, a lysosomal aspartic proteinase, is secreted in the form of enzymatically inactive proenzyme by many types of human breast cancer tissue and exerts mitogenic activity toward these tissues. Flow cytometry was used to test the binding of procathepsin D purified from the secretion of the b