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Possible role of preS2 peptides presented by MHC class I antigen in the pathogensis of chronic hepatitis B

✍ Scribed by Yamauchi, Katsumi; Nakamura, Tetsuo; Yonemitsu, Harumi; Sekiya, Hitomi; Katoh, Jyunko; Obata, Hiroshi


Book ID
122996669
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
279 KB
Volume
17
Category
Article
ISSN
0168-8278

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It has been suggested that cytotoxic T cells are involved in the recognition and lysis of the infected hepatocytes in chronic hepatitis B virus infection, and that the target antigen is probably HBcAg which is displayed on the hepatocyte membrane during active viral replication. However, studies in