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Possible Regulation of FGF Activity by Syndecan, an Integral Membrane Heparan Sulfate Proteoglycan

โœ Scribed by MERTON BERNFIELD; KEVIN C. HOOPER


Book ID
119866707
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
718 KB
Volume
638
Category
Article
ISSN
0890-6564

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Proteinuria in diabetic nephropathy has been correlated with reduction in heparan sulfate proteoglycan (HSPG) content of the glomerular basement membrane. We have previously shown that the underlying mechanism probably involves reduction in the synthesis by glomerular epithelial cells. In this study