On the mechanism of dehydration of a Ξ²-h
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Hyuk-Koo Lee; Howard J. Lambert; Richard L. Schowen
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Article
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1984
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John Wiley and Sons
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English
β 546 KB
The dehydration of the P-hydroxycyclopentanone, 11,16dihydroxy-16-methyl-9-oxo-13-trans-protenoic acid methyl ester, an analogue of prostaglandin El, proceeds with acid catalysis (pH < 3), by uncatalyzed routes (pH N 4 and N 7), and with base catalysis (pH N 5-6 and > 8). Deuterium from the solvent