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Possible occurrence and meaning of lymphocytes bearing autoanti-idiotypic receptors during the immune response

✍ Scribed by N. Tasiaux; R. Leuwenkroon; C. Bruyns; J. Urbain


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
503 KB
Volume
8
Category
Article
ISSN
0014-2980

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✦ Synopsis


Abstract

During an immune response, the increase in binding affinity of antibodies is followed by a fall. Lymphocytes bearing autoanti‐idiotypic receptors were detected during a normal immune response. The kinetics of appearance and disappearance of such lymphocytes led us to propose a network model to explain the changes occurring in antibody properties during an immune response.