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Possible noradrenergic involvement in naloxone potentiation of apomorphine-induced stereotypic climbing in mice

✍ Scribed by Raymond M. Quock; Alan S. Bloom; James A. Sadowski

Book ID
114103191
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
477 KB
Volume
21
Category
Article
ISSN
0091-3057

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The dopaminergic agonist apomorphine produced dose-dependent stereotypic climbing behavior in mice housed in cages with vertical bars. This drug effect was competitively inhibited by systemic pretreatment with the centrally acting dopaminergic antagonist haloperidol but not by microwave irradiation