Molecular targets of botulinum toxin at
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Dorothy D. Whelchel; Tonia M. Brehmer; Paula M. Brooks; Neely Darragh; Julie A.
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Article
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2004
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John Wiley and Sons
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English
β 197 KB
The molecular targets of botulinum neurotoxins (BoNTs) are SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein-receptor) proteins necessary for neurotransmitter release. BoNT are powerful therapeutic agents in the treatment of numerous neurological disorders. The goals of this study