๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Possible mechanisms for the presumed interaction between lithium and neuroleptics

โœ Scribed by L. Von Knorring

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
389 KB
Volume
5
Category
Article
ISSN
0885-6222

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โœฆ Synopsis

All the case reports describing neurotoxicity following combined lithium and haloperidol treatment could well be consistent with lithium toxicity alone. Pharmacokinetic and pharmacological explanations are considered. The effects of co-administered lithium and neuroleptic treatment on fluid balance mechanisms and intracellular lithium concentrations may be associated with increased lithium toxicity.

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