Velo-cardio-facial syndrome (VCFS) is a congenital anomaly characterized by multiple dysmorphisms, cleft palate, cardiac anomalies, and learning disabilities, that results from a microdeletion of chromosome 22q11. An increased prevalence of psychiatric illness has been observed, with both schizophre
Possible locus for bipolar disorder near the dopamine transporter on chromosome 5
โ Scribed by Kelsoe, John R.; Sadovnick, A. Dessa; Kristbjarnarson, Helgi; Bergesch, Patricia; Mroczkowski-Parker, Zofi; Drennan, Michael; Rapaport, Mark H.; Flodman, Pamela; Spence, M. Anne; Remick, Ronald A.
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 968 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
โฆ Synopsis
method (P = 0.001), an affected sib pair method (ESPA, P = 0.0008), and the transmission disequilibrium test (P = 0.024). These results suggest the presence of a susceptibility locus for bipolar disorder near the DAT locus on chromosome 5.
๐ SIMILAR VOLUMES
We attempted to identify a locus for schizophrenia and related disorders in 24 nuclear families of schizophrenic probands using a predefined classification system for affected cases that included those disorders most clearly identified as sharing a genetic relationship with schizophrenia-schizoaffec