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Possible involvement of stem cell factor and endothelin-1 in the emergence of pigmented squamous cell carcinoma in oral mucosa

✍ Scribed by Kazuhito Satomura; Reiko Tokuyama; Yasuhumi Yamasaki; Tetsuya Yuasa; Seiko Tatehara; Naozumi Ishimaru; Yoshio Hayashi; Masaru Nagayama

Book ID
111255081
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
683 KB
Volume
36
Category
Article
ISSN
0904-2512

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## Abstract A high level of plasminogen activator inhibitor‐1 (PAI‐1 or __SERPINE1__) in tumor extracts is a marker of a poor prognosis in human cancers, including oral carcinomas. However, the mechanisms responsible for the upregulation of PAI‐1 in cancers remain unclear. Investigating specific PA