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Possible involvement of protein kinase C in the attenuation of the morphine-induced Straub tail reaction in diabetic mice

✍ Scribed by Masahiro Ohsawa; Junzo Kamei

Book ID: 114016757
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 133 KB
Volume: 362
Category: Article
ISSN: 0014-2999
DOI: 10.1016/s0014-2999(98)00765-1

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Morphine is known to produce a characteristic and reproducible elevation of the tail in mice (Straub tail response). The morphine-induced Straub tail response in mice has been used to evaluate skeletal muscle relaxant (SMR) activity of compounds administered intraperitoneally (i.p.). This model was