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Possible involvement of mast cells in renal fibrosis in patients with IgA nephropathy

✍ Scribed by T. Sakamoto-Ihara; Y. Suzuki; A. Kurusu; M. Yamashita; S. Horikoshi; Y. Tomino


Publisher
SP Birkhäuser Verlag Basel
Year
2007
Tongue
English
Weight
425 KB
Volume
56
Category
Article
ISSN
1420-908X

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The mechanism of mesangial IgA deposition is poorly understood in IgA nephropathy (IgAN). Abnormal glycosylation of carbohydrate moieties in the hinge region of the IgA molecule has recently attracted much attention. In this report, we studied galactosylation and sialylation profiles in κand λ-IgA 1