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Possible involvement of G-proteins in the regulation of striatal dopamine D2 receptor affinity by cholecystokinin octapeptide

✍ Scribed by Xi-Ming Li; Anders Jansson; Ulla-Britt Finnman; Luigi F Agnati; Kjell Fuxe

Book ID
117475491
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
198 KB
Volume
228
Category
Article
ISSN
0304-3940

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am