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Possible involvement of Cyclic-GMP-dependent protein kinase on matrix metalloproteinase-2 expression in rat aortic smooth muscle cells

✍ Scribed by Dey, Nupur B.; Lincoln, Thomas M.

Book ID: 118805596
Publisher: Springer
Year: 2012
Tongue: English
Weight: 578 KB
Volume: 368
Category: Article
ISSN: 0300-8177
DOI: 10.1007/s11010-012-1339-2

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## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor