Possible in vivo modulation of Leu 2a expression on suppressor T cells in active multiple sclerosis

Activation of myelin reactive T cells in

Activation of myelin reactive T cells in multiple sclerosis: A possible role for T cell degeneracy?

✍ Piet Stinissen; Niels Hellings 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB

## Abstract While it is widely accepted that myelin reactive T cells are key players in the immunopathogenesis of multiple sclerosis (MS), the initial triggers that turn on these self‐reactive T‐cells remain to be determined. One mechanism, which is already text book knowledge for a decade, is mole