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Possible implication of Mdm2 as a prognostic marker in invasive laryngeal carcinoma

✍ Scribed by Marcela K. Hassumi-Fukasawa, Fabiana A. Miranda-Camargo, Márcia C. M. Guimarães, Renata T. Simões, Eduardo A. Donadi, Christiane P. Soares, Edson G. Soares

Book ID: 113040043
Publisher: Springer-Verlag
Year: 2012
Tongue: English
Weight: 441 KB
Volume: 269
Category: Article
ISSN: 0302-9530
DOI: 10.1007/s00405-012-1937-3

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## Abstract The HER2 (c‐erbB‐2) receptor is overexpressed in a variety of human malignant tumors and, in breast carcinoma, has been identified as a target for anti‐HER2–directed therapy with the monoclonal antibody (MAb) trastuzumab. The aim of this retrospective study was to evaluate immunohistoch