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Possible Function of Astrocyte Cytochrome P450 in Control of Xenobiotic Phenytoin in the Brain: In Vitro Studies on Murine Astrocyte Primary Cultures

✍ Scribed by Ralf Peter Meyer; Rolf Knoth; Emil Schiltz; Benedikt Volk


Book ID
115607407
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
219 KB
Volume
167
Category
Article
ISSN
0014-4886

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Studies on cytochrome P450 2B (CYP2B) in the brain have essentially been focused on protein characterization and regional distribution. Due to the high sequence homology between the closely related CYP2B1 and 2B2 isoforms and the low amounts of the corresponding mRNAs few efforts have been made to a