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Possible cytokine mechanism of increased megakaryocytic proliferation in 5q- syndrome

✍ Scribed by Yücel Üstündaǧ; Ibrahim C. Haznedaroǧlu; Osman Özcebe; Semra Dündar; ŞErafettin Kirazli


Book ID
101318792
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
144 KB
Volume
52
Category
Article
ISSN
0361-8609

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In this work, we report spontaneous chromosomal breakpoints and fragile site expression induced by 5-fluorodeoxyuridine (FdUrd) and FdUrd plus caffeine in a family with Bloom's syndrome (BS) and 2 healthy donors. Standard and G-banded metaphases from each individual and each treatment were analyzed.