Possible connection between lipophilicity and steric substituent constants

✍ Scribed by Miloň Tichy̌

• Book ID: 104579605
• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 364 KB
• Volume: 16
• Category: Article
• ISSN: 0020-7608
• DOI: 10.1002/qua.560160309

✦ Synopsis

Abstract

The steric constants E~s~ and ν have the greatest chance of being independent of lipophilic substituent constants. There is a high probability among hydrocarbon substituents that the steric constants correlate with the lipophilic ones, while in the case of polar substituents the probability is low.