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Possibilities for tailored and targeted therapy in paediatric acute myeloid leukaemia

✍ Scribed by Ch. M. Zwaan; G. J. L. Kaspers

Book ID: 108672850
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 235 KB
Volume: 127
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2004.05167.x

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## Abstract Telomeres are specialized structures localized at the end of human chromosomes. Due to the end replication problem, each cell division results in a loss of telomeric repeats in normal somatic cells. In germ line and stem cells, the multicomponent enzyme telomerase maintains the length o