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Positively-charged microemulsion for improving the oral bioavailability of alendronate: in-vitro and in-vivo assessment

โœ Scribed by Jian Meng; Liandong Hu

Book ID
118111474
Publisher
Pharmaceutical Press
Year
2011
Tongue
English
Weight
571 KB
Volume
63
Category
Article
ISSN
2042-7158

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Oral delivery of hydrophilic, ionisable drugs remains a major challenge in drug development and a number of active pharmaceuticals fail to reach the market of oral drugs because of a lack of absorption and/or stability issues. One possible approach to improving the bioavailability of such drug candi